How effective are antidepressants really? What is behind the widely accepted serotonin hypothesis of depression? And what is the current state of research on the biological foundations and treatment approaches?

Thomas Padberg addresses these questions in his article in the *Psychotherapeutenjournal*. He critically examines the serotonin hypothesis, which has long been considered a standard explanation for the development of depression, and presents current research findings on the effectiveness of antidepressants. Both brain-related metabolic aspects and psychosocial factors are taken into account.

Read the full article in:

Psychotherapeutenjournal, Issue 1/19

This article offers fascinating insights into the debate on biochemical models of depression and highlights both the complexity of the condition and the multifaceted nature of modern therapeutic approaches.